DNA is the correct answer but next time put answer choices so that people can better answer your questions. Thanks!
Sickle cell disease is a hereditary disease seen most often among people of African ancestry. Caused by mutations in one of the genes that encode the hemoglobin protein, the disease is inherited as an autosomal recessive trait.
Latitude influences your weather by determining which type of weather systems will cross the area and how frequently, elevation influences your weather because higher elevations have lower air pressure than lower elevations, thus allowing the air to be colder on average. Local geography influences your weather due to different areas being nearby mountain ranges, bodies of water, and other things that can create or dissimilate different weather systems.
It all just depends on what genes they carry. You can create a Punnet Square to determine the percentage of obtaining a specific disease.
Answer:
weather is more of how the force of wind or how tough it is outside. climate is like the tempature of the area