Answer:
Explanation:
DNA polymerase is an enzyme that helps in the synthesis of new strands of DNA. It is found in both prokaryote and eukaryotes. In prokaryotes, there are 3 types of DNA polymerase and more DNA polymerase found in eukaryotes.
The 3 types of DNA polymerase are DNA polymerase I, DNA polymerase II, DNA polymerase III. The DNA pol I and DNA pol II helps in DNA repair rather than DNA replication. The DNA pol III is the major enzyme that initiates the replication.
DNA polymerase III is a multisubunit enzyme that functions as a dimer of these multiple subunits. The DNA polymerase enzyme has 3 significant enzymatic activities -
All DNA polymerase direct the synthesis of DNA from 3' to 5' end.
It possesses 3' to 5' exonuclease activity. It also helps in proofreading activity by replacing the incorrect nucleotides with the correct base sequence.
Some DNA polymerase has a 5' to 3' exonuclease activity. It is found in the lagging strand.
DNA polymerase is not able to initiate DNA synthesis alone. They need a free 3' end, where the enzyme can add new nucleotides. It means they require 2 primers to initiate the DNA replication in both the direction.
The strands act as complementary to the DNA polymerase. The DNA polymerase adds new strands continuously in 5' to 3' direction in the leading strand. While in lagging strand short fragments of DNA formed. Later they attached by DNA ligase.
DNA polymerase also needs RNA polymerase in some cases to start replication. Such a process is called reverse transcription.
Prokaryotes don’t have any membrane bound-organelles but they have DNA, a cell membrane and ribosomes
The vector that would be the
best choice for cystic fibrosis gene therapy is adeno-associated virus for it
has valuable reasons. First, it is huge enough to carry the gene, second, it
will infect the right type of tissue, third, it will not cause an immune
response and lastly, it infects the particular cells that divide irregularly. Therefore,
this vector will definitely treat cystic fibrosis for it can target affected
cells, which is a great help in the normal functioning of an organ.
I think it's number 3 .......
Answer:
The wechsler intelligence scale for children (WISC) is a good indicator of innate "genetic" ability for children of six to sixteen years old.
Explanation:
Wechsler Intelligence Scale for Children (WISC) is basically a system of testing IQ of children from six to sixteen years old. This testing was created by David Wechsler, who stated that intelligence is a global quality and it should be reflected in children's verbal as well as non-verbal abilities.
This testing system is used by schools for several purposes:
• To evaluate the performance of kids during placement process.
• It is also used to evaluate abilities of dis-abled children or deferentially able children.
• IQ scores from WISC can be used to diagnose the problems of the children such as mental re-tardation or some specific learning dis-ability. It can also be used to determine the problems of the children who face hyperactivity or attention deficiency.
• In addition, the test can also diagnose brain related and neuro-psychological disorder.
Point to remember:
The WISC system is not useful to determine the extreme form of intelligence like IQ below 40 and above 160. Wechsler himself focused on this point many times that test is not adequate for children with IQs of below 70 or above 130. Despite of this fact, people use this test to determine the intelligence of deferentially able children who usually have IQ above 130 that is not very appropriate thing.
<em>Note:</em><em> This answer is very generic based on the statement of the question. If you have some specific options of the questions, please post it again with them or comment. Thank you.</em>