the Nucleus
Explanation:
Known as the cell's “command center,” the nucleus is a large organelle that stores the cell's DNA (deoxyribonucleic acid). The nucleus controls all of the cell's activities, such as growth and metabolism, using the DNA's genetic information.
Answer: False
Explanation:
Pathogens can be transmitted in many ways. It can spread by direct contact, indirect contact, or by vectors.
The mode of transmission can be skin contact, airborne particles, touching a surface, bodily fluids, touched by an infected person.
The mode of transmission can be vector that carries disease and helps in disease transmission.
So, the pathogens can be transmitted by direct contact, indirect contact or by vectors and by many more ways.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
so, an example of something that might not be a substrate is the animal itself.
explanation
substrate is the surface of where living animals, live.
sorry if this doesnt help.
HAPPY ALMOST HALLOWEEN