Emil Kraeplin developer the system that is the foundation for our modern classification system
Answer:
Neurodegeneration
Explanation:
The term neurodegeneration refers to a group of disorders which are characterized by a progressive waste of function or structure of neurons, that in worst cases can include death of neaurons.
Many neurodegenerative disorders such as Parkinson's disease,– including amyotrophic lateral sclerosis, Huntington's disease and Alzheimer's disease can occur due to neurodegeneration.
Neurodegeneration can manifest itself in various forms such as lack of physical and intellectual abilities like inability to use muscles or memory loss. These disorders cannot be completely cured and ultimately lead to the death of neurons.
As mentioned in the question, the person suffers from progressive loss of intellectual and physical abilities that has occurred over the course of a long period of time. Therefore, it is most probable that he is having some neurodegenerative disorder.
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The physical barrier that the mRNA must pass is the nuclear membrane.
The process of gene expression involves two main stages; transcription ; the production of messenger RNA by the enzyme RNA polymerase, and the processing of the mRNA molecule. Then the process of translation which takes place outside the nucleus, therefore the mRNA must cross the nuclear membrane to enter the cytoplasm.