MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.
A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.
The checkpoints during mitosis are:
- At the end of stage G1 and before S.
- Before anaphase in mitosis.
- DNA damage checkpoints in G1, S or G2.
The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.
That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.
Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
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Explanation:
El número de animales salvajes que viven en la Tierra va camino de disminuir en dos tercios para el año 2020, según el informe Planeta Vivo de WWF, en el que se señala que la extinción parcial de especies está destruyendo el sustento biológico del que depende la humanidad. Este informe, el más completo realizado hasta la fecha, indica que las poblaciones de animales se desplomaron en un 58% entre 1970 y 2012 y todo apunta a que esta pérdida podrá alcanzar el 67% en 2020.
Because as natural selection occurs and species mate and create offspring this leads to a change in DNA which can lead to new species or evolutionists versions of that species
Maintain homeostasis - eg. blood sugar control by insulin and glucagon.<span>
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True, a lot of cultivated fields use fertilizers that can be harmful to fish