The outer layer contains endotoxins that cause these symptoms
Explanation:
Endotoxins are lipopolysaccharides complex associated with the outer membrane of Gram-negative bacteria (e.g., Escherichia coli, Salmonella, Pseudomonas, Neisseria, Shigella, etc). These endotoxins are well-known to cause inflammation and fever, which are natural responses of the immune system. Inflammation stimulates white blood cells (leukocytes) to attack pathogenic harmful microorganisms. Moreover, the increased body temperature (fever) also can inhibit the growth of many harmful microorganisms since human pathogens are mesophiles, i.e., they exhibit an optimum growth at moderate temperature (35 °C).
Some studies have shown that the use of insulin is associated with an increased risk of cardiovascular events, cancer and all-cause mortality in comparison with other glucose-lowering therapies.
