Cross over is the first way genes are shuffled to give rise to genetic diversity. Cross over takes place in sexual reproduction. The normal way that cross over occurs is chromosomes line up side by side and break off pieces of themselves, then trade those pieces with each other.
If they break the pieces at the same locus in the sequence of base pairs, the result is an exchange of genes called genetic recombination and it ensures that the daughter cells produced have a different genetic makeup from the parent cell and thus diversity occurs.
The mutation is a change in just one nucleotide in the gene for hemogloblin.
Mutation would be the best answer.
The number of protons and elctrons adds up to the mass number