Answer: Smallpox
Explanation: Small pox is an ancient disease which is caused by the Virus named as Variola virus. Early symptoms are fatigue and high fever.
The virus then after produces rash on faces arms and legs. The spots gets filled with fluid and pus and in later stages it turned into crust.
This crust eventually dried and falls off. It was fatal in almost 30% of the cases.
It eradicated by a collaborative global vaccination program which was led by WHO.
Changes within the uterus