Answer:
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke.
DNA is a dynamic and adaptable molecule. As such, the nucleotide sequences found within it are subject to change as the result of a phenomenon called mutation. Depending on how a particular mutation modifies an organism's genetic makeup, it can prove harmless, helpful, or even hurtful.
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It can affect the biological catalyst called enzymes. This is because the acidic ph will cause the enzymes to change shape also known as denature.
Antibiotic resistance happens when an antibiotic lost its ability in controlling or killing bacterial growth. At this moment the bacteria are already resistant to the antibiotic and are multiplying even though the drug is present. This is a natural phenomenon.