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Cocaine selectively blocks sodium channels which is the mechanism that leads to local anesthetic effects.
Voltage gated sodium channels play very important roles in the body as they are responsible for action initiation and propagation in excitable cells, such as nerves, muscles and neuroendocrine cells. Like other sodium ion channels blockers such as lidocaine, Cocaine selectively blocks sodium ion channels which denies entry of sodium ions in the cell, thus leading to local anesthetic effects.
We can calculate the final temperature from this formula :
when Tf = (V1* T1) +(V2* T2) / (V1+ V2)
when V1 is the first volume of water = 5 L
and V2 is the second volume of water = 60 L
and T1 is the first temperature of water in Kelvin = 80 °C +273 = 353 K
and T2 is the second temperature of water in Kelvin = 30°C + 273= 303 K
and Tf is the final temperature of water in Kelvin
so, by substitution:
Tf = (5 L * 353 K ) + ( 60 L * 303 K) / ( 5 L + 60 L)
= 1765 + 18180 / 65 L
= 306 K
= 306 -273 = 33° C
Answer:
NiO Does Not Dissolve In An Aqueous Solution Of NaNO3.
Explanation:
