I’m not sure if this is exactly what ur asking, but vitamin c, zinc, and copper are needed
P450scc or cholesterol side chain cleavage enzyme is an enzyme that converts cholesterol into pregnenolone (the precursor for steroids). The kinds of steroid hormones are mineralocorticoids (i.e. aldosterone) glucocorticoids (i.e. cortisol), and sex steroids (i.e. testosterone, estrogen). In the event where P450scc is blocked, then there will be no production of mineralocorticoids, glucocorticoids, and sex steroids. There will be no production of aldosterone, cortisol, estradiol, testosterone, and progesterone. This disease is called Lipoid Congenital Adrenal Hyperplasia.
They have been in the Northern and Southern polar regions, and not within the inner part of earth, maybe due to there location
A) after 1911 gradual increase in deaths pattern explains that smoking causes cancer !
b) after 2001 , the graph will continue decreasing, because of the steps taken by government, the steps by people itself !! that all helps in decreasing deaths and cancer number after 2001 !