Every cell of the organism has the same DNA sequence and same genes. However, not all genes are expressed in every single cell at the same time. Only those genes necessary for a specialised function of a specialised cell are expressed in the specialised cell. For example, skin cells have some different proteins than nerve cells. Genes responsible for those "skin proteins" are activated in skin cells and are turned off in nerve cells.
Genotype or Phenotype relationships
I think that’s substitution
Answer:
Homeostasis is defined as the state of body in which body maintains several chemical and physical changes inside the body affected by external factors.
Negative feedback loop includes a sensor, stimulus, control center, and effector which is used to control homeostasis.
A negative feedback loop is a reaction that reduce an excessive response and maintain the functions within the normal range. for example: if temperature and blood glucose level increases in the body, negative feedback loops control both the variables and maintain homeostasis.
Hence, negative feedback loops used to control body homeostasis.