Answer:
B. Early Eukaryotic cells engulfed mitochondria and chloroplasts
Explanation:
Mitochondria and Chloroplast are organelle that are found in cells of higher animals. Chloroplast are found almost exclusively in plants and mitochondria is found in animal cells. The function of these organelles are to produce energy to the cells, and by extension, the organism that they live in.
Unique features of these organelles show that they have their own DNA and divide and multiply on their own. This strongly suggest that they were once free living prokaryotes and were engulfed by larger cells and a symbiotic relationship began.
As time progressed, these prokaryotes did not require all of their genetic information and this was removed from their system. They kept essential genes and regulatory bodies separate that they needed for their maintenance and function that they provide.
The factors were latitude, elevation, nearby water, and ocean curents. All of these factors affect earth's climate.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
#SPJ4
Analytical balance is your answer
It is an essential element for plant life, but when there is too much of it in water, it can speed up eutrophication (a reduction in dissolved oxygen in water bodies caused by an increase of mineral and organic nutrients) of rivers and lakes. Soil erosion is a major contributor of phosphorus to streams.