Answer:
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke.
DNA is a dynamic and adaptable molecule. As such, the nucleotide sequences found within it are subject to change as the result of a phenomenon called mutation. Depending on how a particular mutation modifies an organism's genetic makeup, it can prove harmless, helpful, or even hurtful.
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Your answer is the peripheral proteins. Its on the inner or outer surface of the phospholipid bilayer, but not embedded in its hydrophobic core.
By pushing on the top of it and the water or substance will get into it