connections between cancer patients hospitalized for symptoms and healthcare utilization and patient-reported care satisfaction
What is healthcare?
It offers comprehensive care for health requirements across the lifespan, not only for a collection of particular disorders. Primary health care guarantees that patients receive high-quality, all-encompassing care that is as close as practical to their daily environments, spanning from promotion and prevention through treatment, rehabilitation, and palliative care.
From September 2014 to April 2017, we prospectively enrolled individuals who had cancer and unanticipated hospitalizations. We evaluated patients' physical, psychological, and emotional symptoms at the time of admission, as well as their satisfaction with their care (FAMCARE items: satisfaction with care coordination and timeliness of symptom treatment). We used regression models to find characteristics that affect care satisfaction and relationships between satisfaction and symptom load and length of hospital stay (LOS).
The majority of the 1,576 participants expressed "satisfaction" or "very satisfaction" with care coordination (90%) and the promptness of symptom treatment (89%).
High levels of care satisfaction are reported by cancer patients who are hospitalized, and these levels are associated with older age and admission to an oncology service. The significance of enhancing symptom management and care coordination in this population is highlighted by the relationships between higher care satisfaction, lower symptom load, and shorter hospital LOS.
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Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
I would say boston or chicago personally
Answer:
It authorized grants to develop a comprehensive EMS system throughout the country, for feasibility studies and planning, for the establishment and initial operation of EMS systems, and for the expansion and improvement of current systems. To have trained personnel respond quickly and provide emergency care on the scene, during transport, and at the hospital.
Explanation:
