Answer:
When evaluating the relationship of George and Lennie, keep in mind the influential external factors. The setting takes place during the time of the Great Depression and the Dust bowl. Lennie and George are both migrant workers and depend on farm work for money at a time when America's economy was the weakest and its farms were struggling to keep animals and crops alive. In addition, the Unites States is filled with intense prejudice towards races, sexes, and outcasts. There are a number of relationship pairs to evaluate throughout the story so keep the setting complications in mind.
Through figurative language and characterization used in chapter one, Steinbeck reveals the characteristics of both George and Lennie. Lennie has a mental disability and is a regular burden on George; he has lost jobs because of his inability to control his strength and is regularly badgering George with questions. Because of his strength, however, Lennie is able to impress farm owners who desire capable physical laborers. On the other hand, George has the wit and instinct to navigate from farm to farm and find new areas to work.
While George sacrifices job stability and independence, he gains companionship at a time when the rest of world is indifferent to him. Likewise, Lennie sacrifices some personal dignity (George regularly casts crude, demeaning remarks on Lennie) and gains a protector, provider, and friend.