Bloom syndrome (BS) is a rare autosomal recessive disorder characterized by growth deficiency, immunodeficiency, genomic instability, and the early development of cancers of many types. BLM, the protein encoded by BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells. BLM encodes a DNA helicase, and proteins from three missense alleles lack displacement activity. BLM transfected into BS cells reduces the frequency of sister chromatid exchanges and restores BLM in the nucleus. Missense alleles fail to reduce the sister chromatid exchanges in transfected BS cells or restore the normal nuclear pattern. BLM complements a phenotype of a Saccharomyces cerevisiae sgs1 top3 strain, and the missense alleles do not. This work demonstrates the importance of the enzymatic activity of BLM for its function and nuclear localization pattern.
<u><em>What DNA sequence were the researchers trying to detect? </em></u>
<u><em>Are you referring to the choices below?</em></u>
Answer:
By providing oxygen to your cells
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Given what we know, we can confirm that the two organisms most closely related would be the human and the gorilla.
<h3>Why are the Gorilla and Human the most closely related?</h3>
Using only the information given from the diagram, we can say that gorillas and humans are the most closely related. Although the turtle and the chicken also share the same genetic similarities in the diagram, the human and the gorilla also share physical aspects between them, making them more related than the previous group.
Therefore, given that they share genetic and physical aspects, we can confirm that the two organisms most closely related would be the human and the gorilla.
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Answer:
Explanation:
The observed frequency of the double crossovers (DCOs) is 20/1000, or 0.02. If there is no interference then this will be the same as the expected, which is just the product of the single crossover frequencies, that is, SCO frequency (a-b) x SCO freq. (b-c) = 0.02.
(a) Any combination of map distances whose product (a-b) x (b-c) = 0.02 is possible. However, three are most likely:
a 20 mu b 10 mu c
a 10 mu b 20 mu c
a 14.14 mu b 14.14 mu c
(b) The distances would be exactly the same.
(c) The expected number of DCO progeny would be 17.
Answer:
Euglena is a photosynthetic euglenoid with at least 150 described species. The cells are cylindrical with a rounded anterior and tapered posterior.
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