A variation of the acetamidomalonate synthesis can be used to synthesize serine. The process involves the following steps: Ethox
ide ion deprotonates diethyl acetamidomalonate, forming enolate anion 1; Enolate anion 1 makes a nucleophilic attack on formaldehyde, forming tetrahedral intermediate 2; Protonation of the oxyanion forms alcohol 3; Acid hydrolysis yields dicarboxyamino alcohol 4; Decarboxylation leads to the final amino acid. Write out the mechanism on a separate sheet of paper, and then draw the structure of dicarboxyamino alcohol 4.
1 answer:
Answer:
See detailed mechanism in the image attached
Explanation:
The mechanism shown in detail below is the synthesis of serine in steps.
The first step is the attack of the ethoxide ion base on the diethyl acetamidomalonate substrate giving the enolate and formaldehyde.
The second step is the protonation of the oxyanion from (1) above to form an alcohol as shown.
Acid hydrolysis of the alcohol formed in (3) above yields a tetrahedral intermediate, a dicarboxyamino alcohol.
Decarboxylation of this dicarboxyamino alcohol yields serine, the final product as shown in the image attached.
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7 × 10² pounds of Cl₂ would be produced in a typical 8-h operating day.
<h3>What is Stoichiometry ?</h3>Stoichiometry helps us use the balanced chemical equation to measures quantitative relationships and it is to calculate the amount of products and reactants that are given in a reaction.
<h3>What is Balanced chemical equation ?</h3>The balanced chemical equation is the equation in which the number of atoms on the reactants side is equal to the number of atoms on the product side in an equation.
2Cl⁻ (aq) → Cl (g) + 2e⁻
According to stoichiometry, moles of Cl₂
= 4477 moles
Pounds Cl₂
= 7 × 10² lb
Thus from the above conclusion we can say that 7 × 10² pounds of Cl₂ would be produced in a typical 8-h operating day.
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