Answer:
The Various Kinases that is activated after the breaks in DNA is after the activation of ATM serine threonine kinase which helps in phosphorylation of other DNA replication check proteins, p53 protein (tumor suppressor protein) etc.
Explanation:
ATM activated by MRN complex at the site of DNA double stranded breaks by phosphorylation. MRN complex activity on ATM induces a conformational change in ATM kinase. So it can bind to its various substrate molecules that helps in DNA replication cycle arrest.
ATM phosphorylates CHK2 protein a product of CHEK2 gene, also known as effector kinases that phosphorylates and helps in deactivation of cyclin dependent kinases (CDKs) that helps in the prevention of progression of mitotic phase.
ATM also phosphorylates the inhibitors of p53 proteins which leads to the overexpression of p21, an inhibitor of (CDKs).
Answer:
pH = 3.215
Explanation:
From the given information;
Using the equation for the dilution of a stock solution:
Since moles of C5H5N = moles of HNO3
Then:
The reaction between C5H5NH and H2O is as follows:
⇄ 
Now, the next step is to draw out the I.C.E table.
⇄
I 0.06333 0 0
C - x x x
E 0.06333 -x x x
![K_a = \dfrac{[C_5H_5N][H_3O^+] }{[C_5H_5N^+H] } \\ \\ 5.8824 \times 10^{-6} = \dfrac{x^2}{0.06333 - x}](https://tex.z-dn.net/?f=K_a%20%3D%20%5Cdfrac%7B%5BC_5H_5N%5D%5BH_3O%5E%2B%5D%20%7D%7B%5BC_5H_5N%5E%2BH%5D%20%7D%20%20%5C%5C%20%5C%5C%20%205.8824%20%5Ctimes%2010%5E%7B-6%7D%20%3D%20%5Cdfrac%7Bx%5E2%7D%7B0.06333%20-%20x%7D)
Assuming x < 0.06333
Then
![[H_3O^+] = x = 6.1035 \times 10^{-4} \ M \\ \\ pH = -log (6.1035 \times 10^{-4}) \\ \\ \mathbf{\\ pH = 3.215}](https://tex.z-dn.net/?f=%5BH_3O%5E%2B%5D%20%3D%20%20x%20%3D%206.1035%20%5Ctimes%2010%5E%7B-4%7D%20%5C%20M%20%20%5C%5C%20%5C%5C%20%20pH%20%3D%20-log%20%286.1035%20%5Ctimes%2010%5E%7B-4%7D%29%20%5C%5C%20%5C%5C%20%5Cmathbf%7B%5C%5C%20pH%20%3D%203.215%7D)
Answer:A. The release of calcium ions causes myosin and actin to attach to each other.
The contraction of skeletal muscles takes place by induction of a nerve impulse, which produces a movement and the interaction of the filaments containing proteins named as actin and myosin. This interaction of filaments is regulated by proteins called tropomyosin and troponin present on the actin filaments. The motor nerve causes the depolarization of the muscle membrane sarcolemma. This triggers the sarcoplasmic reticulum to release calcium ions. This calcium binds to troponin and thus allows the tropomyosine strand on the actin filament to displace so that the part of the actin where myosine head needs to be attached remain uncovered. Binding of the actin myosine filament results in contraction.
Hence, the release of calcium ions causes myosin and actin to attach to each other causes muscle contraction.
Political science is a social science discipline that deals with systems of government and the analysis of political activity and political behavior. It deals extensively with the theory and practice of politics which is commonly thought of as the determining of the distribution of power and resources.
