If you intend to study Taxol, you'd be most interested in cells during metaphase/anaphase. This is because Taxol deleteriously affects the ability of cancer cells to properly assemble a mitotic spindle, pass the metaphase/anaphase checkpoint, and produce progeny.
The fragility of cancer cells when they undergo division serves as a critical intervention point in chemotherapy. ... Despite being the shortest phase of the cell-cycle, mitosis ... Therefore, there is a strong interest in developing novel drugs that do not affect .... cells. Plk1 is the most thoroughly studied member.
