The correct answer would be D.
After many generations, only those with genes suitable to live in harsh environments can live. These genes are passed onto their offspring and then we see a rise in antibiotic resistant strains of bacteria such as Methicillin Resistant Staphylococcus Aureus (MRSA).
Explanation:
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When testing a hypothesis, scientists use repeated trials and replication to make sure that they get the same answer each time, and that it isn't just a lucky guess the first time. They need be sure that the answer to their hypothesis is 100% the same every time.