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If phospholipid bilayer diffusion is normally negligible, there will be tissues (largely lacking in transporters that may be expressed elsewhere) which, despite the relative functional similarity of their phospholipids, are very poor at taking up drugs: the blood–brain [33], blood–testis [34], and blood–retina
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Answer: A missense mutation changes the identity of a codon from one amino acid to another, resulting in a change to the protein primary structure. A silent mutation occurs when a mutation does not change the amino acid coded for by that codon.
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