The right answer is changing an organism’s genes to make new molecules.
Biotechnology is the product of scientific research in areas such as biology, microbiology, biochemistry, biophysics, genetics, molecular biology, computer science. They intervene from engineering to the transformation of matter by biological agents in order to produce "goods and services".
For example, the manufacture of insulin: For a micro-organism such as a cell or a bacterium to produce a molecule such as insulin, it must be genetically modified.
Channel and carrier proteins are both considered facilitated diffusion. We also know that materials do not like to go against the concentration gradient so we can eliminate B.