The ancient Babylon (located in west Asia), ancient Egypt (located in north Africa), the ancient India, which is located in the South Asia and China which is located in east Asia.
In my view purpose and point of view are very important when writing a biography.
It represents Lady Macbeth's malaise and guilt awakening and driving her to insanity. In this scene, she "sees" blood on her hands, a metaphor for her guilt, and it cannot be washed off- the sin cannot be undone. After this scene, Lady Macbeth's strength runs out and is overcome with guilt to the point that she commits suicide.