Familial hypercholesterolemia, an autosomal dominant disease, is five times more frequent in the afrikaner population of south a

Question

2 years ago

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Familial hypercholesterolemia, an autosomal dominant disease, is five times more frequent in the afrikaner population of south a

frica than in the original population of europe from which the ancestors to the afrikaners immigrated. what does this demonstrate?

Biology

2 answers:

IgorLugansk [536] · Answer 1 · 2022-03-08T15:41:43+03:00

This represents the example of founder effect.

The founder effect is a term in genetics that describes the loss of genetic variation as a result of new population formation by a very small number of individuals from a larger population. Small group of migrants (the afrikaner population of south Africa) that is not genetically representative of the larger population (Europe population) forms a new population with lower genetic variation.

vampirchik [111] · Answer 2 · 2022-03-08T17:43:14+03:00

Answer: Founder effect.

Explanation:

The founder effect is caused when a small group of individuals becomes separated from a larger population and move into a new area. This smaller population, moving to a new area forms the founder population.

Since a new population is established from a smaller population it leads to a loss of genetic variation and, this effect is known as founder effect and this is the reason why Familial hypercholesterolemia is more frequent in the afrikaner population