Answer:
-Histamine binds extracellularly to the H1 receptor.
-When histamine binds to the H1 receptor. the receptor undergoes a conformation change and binds the inactive G protein.
-Once the G protein is active, it binds to the enzyme phospholipase C, activating it.
-Histamine is likely hydrophilic.
When histamine encounters a target cell, it binds extracellularly to the H1 receptor, causing a change in the shape of the receptor. This change in shape allows the G protein to bind to the H1 receptor, causing a GTP molecule to displace a GDP molecule and activating the G protein. The active G protein dissociates from the H1 receptor and binds to the enzyme phospholipase C, activating it. The active phospholipase C triggers a cellular response. The G protein then functions as a GTPase and hydrolyzes the GTP to GDP. The G protein dissociates from the enzyme and is inactive again and ready for reuse.
Explanation:
Answer:
DNA replication
Explanation:
Synthesis is the stage characterized by DNA replication. It is after the G1 phase
<span>Tropics
A lot of rain falls there, so the possibility of acid rain and smog which can be carried by warm humid air can also form. </span>
Answer: Growth refers to an increase in physical size of whole or any of its part and can be measured. Development refers to the qualitative changes in the organism as whole. Development is a continuous process through which physical, emotional and intellectual changes occur.
Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
Learn more about the adeno-associated virus (AAV) with the help of the given link:
brainly.com/question/28205495
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