Answer: adenylyl cyclase inositol triphosphate mainly known as IP3 causes the release of Calcium ions directly from the inracellular stores and causea contraction.
Explanation:
IP3, inositol phosphate is a second messenger a signaling molecule. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by an enzyme phospholipase C.
IP3 binds to the calcium channels and opens Ca2+ channels that are embedded in the ER membrane, releasing Ca2+ into the cytosol. Calcium ions released may cause contraction and regulate the Ca2+ channels in the membranes.
Answer:
example of active transport is the sodium-potassium pump, which moves sodium ions to the outside of the cell and potassium ions to the inside of the cell.
C. The lynx population crashes due to their food source being gone.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
You didnt even gave a question.Sorry but i cant answer.
