Question

A sample of the amino acid tyrosine is barely soluble in water. Would a peptide containing only a string of Tyr residues be more or less soluble, assuming the total number of Tyr groups remains constant? Explain.

Answer 1

Answer:

Tyrosine is a polar and aromatic compound. its side chain acidity and basicity is neutral

if a peptide contain only a string of tyrosine residue especially l tyrosine the solubility increases more

Explanation:

even tyrosine number remains constant, tyrosine containing peptide will be more soluble. This peptide is soluble in 1 M HCl (100 mg/ml), with heating. The solubility in water (25 °C) is 0.45 mg/ml in the pH range 3.2 - 7.5.

2.0 mg/ml; at pH 9.5, the solubility is 1.4 mg/ml; and at pH 10, the solubility is 3.8 mg/ml.