Answer: For three traits inherited in a dominant/recessive pattern, the probability of an offspring in a trihybrid cross between parents heterozygous for all three traits to be recessive at exactly two of the three loci is 23/64.
Explanation: Let A, B and C represent the dominant alleles and a, b and c represent the recessive alleles. The genotype of each of the parent will be AaBbCc since it has been said to be heterozygous for all the three traits. There are eight (8) possible different types of gametes from each of the genotype. This can be calculated using 2^n where n is the number of heterozygous loci.
The number of heterozygous loci in the genotype AaBbCc is three (3). 2^3 = 8. The gametes are;
ABC
ABc
AbC
Abc
aBC
aBc
abC and
abc.
Therefore, sixty-four possible offsprings are expected from the cross AaBbCc x AaBbCc.
Out of these offsprings, twenty-three (23) are expected to be heterozygous at two loci as boldly shown in the attached image.
Answer:
How Mutations Can Lead to Human Evolution?
Explanation:
A mutation is the random change in the nucleotide sequence or in the DNA organization (genotype) of a living being, [1] that produces a variation in its characteristics and that is not necessarily transmitted to the offspring. It occurs spontaneously and suddenly or due to the action of mutagens. This change will be present in a small proportion of the population (variant) or the organism (mutation). The genetic unit capable of mutating is the gene, the unit of hereditary information that is part of DNA.
In multicellular beings, mutations can only be inherited when they affect reproductive cells. A consequence of mutations can be, for example, a genetic disease. However, although they may seem harmful in the short term, mutations are essential to our long-term existence. Without mutation there would be no change, and without change life could not evolve.
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