Answer:
Speech therapy and hearing aids may be required
Explanation:
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer: D) precapillary sphincters relax.
Explanation:
Blood flow to a tissue will decrease if precapillary sphincters relax as, capillaries provides glucose and oxygen to the cells and allows blood to flow through it when the muscle ring known as the precapillary Sphincters get relaxed. The blood flow is stopped when the precapillary sphincters constrict flow of blood. As, certain chemical signals causes feeder arterioles to dilate and bring more blood into local areas then, it causes precapillary sphincters to relax.
Anti fungal medication will help bob the most. Because the anti fungal medication is a treatment for invasive pulmonary aspergillosis.
Answer:
_measure intelligence.
Explanation:
Binet and his student Simon first created it because they were asked by the French government to come up with a way to identify children who were slow/behind. So, they invented a scale called the Binet Simon scale dedicated to measuring intelligence.
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