The specific heat capacity represents the amount of energy, in joules, that it takes to raise the temperature of one gram of a given substance by one degree Celsius. Put more simply, the amount of energy it takes to raise a quantity of water by one degree Celsius would raise an equivalent quantity of sand by a little over 14 degrees. Likewise, sand does not need to lose nearly as much energy as water to produce equivalent cooling. Since it "holds" a lot less energy, it cools down much faster than sand.
Indeed, liquid water has an unusually high specific heat capacity. Because it is much less prone to temperature swings than other common substances, large bodies of water often work to moderate temperatures in a region. This helps to explain, for example, why average temperatures fluctuate very little over the year in San Francisco, a city whose climate is heavily influenced by the water that nearly surrounds it.
Answer:
Isotonic contractions maintain constant tension in the muscle as the muscle changes length. This can occur only when a muscle's maximal force of contraction exceeds the total load on the muscle. Isotonic muscle contractions can be either concentric (muscle shortens) or eccentric (muscle lengthens).
The point at which the toxin would interrupt normal cell signalling in the pathway is the signal amplification.
This is because of the G-protein uncoupling and inhibition of signal amplification by pertusis toxin. Pertusis toxin released by the bacteria Bordetella pertusis and prevents signal that is amplifying from the protein. The G-protein coordinates the interaction between membrane bound receptor proteins and the effector proteins involved in the intracellular signalling. The toxin promotes the uncoupling of this heterotrimetric protein and also inhibits the amplification thus preventing the interaction of the receptor proteins and the second messengers.