The relationship between surface area and cell volume is an important factor in cell diffusion efficiency because it interferes with the rate at which the cell is able to incorporate substances and conduct them at its center. That is, cells need to absorb substances such as nutrients, ATP, among others, a larger cell volume would result in a larger surface area and this would increase the cell's need to absorb nutrients. For this reason, the correct alternative to your question is the letter C.
As ribosomes make their proteins, they may attach to the rough ER and insert the protein into the interior of the ER. The ER then begins folding the new proteins and transports them to areas in which chemical processing takes place