There are four monoclonal antibodies (MAB) which specifically recognize double-stranded RNA (dsRNA) together with their use in new methods for detecting and characterizing dsRNA in unfractionated nucleic acid extracts. The specificity of the antibodies was analyzed using a panel of 27 different synthetic and naturally occurring nucleic acids. All four antibodies reacted in a highly specific manner with long dsRNA helices, irrespective of their sequence; no binding to single-stranded RNA homopolymers or to DNA or RNA-DNA hybrids were observed.
Monoclonal antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes.
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Complementary DNA (cDNA) is a DNA copy of a messenger RNA (mRNA) molecule produced by reverse transcriptase, a DNA polymerase that can use either DNA or RNA as a template.
If we had 263 ml of mercury (volume) the density of the mercury is 13.55
g/cm”
Mass = Density x Volume (use image attached as guide)
Mass = 263 x 13.55 = 3563.65
Your mass should be 3563.65
Answer:
Three different kinds of muscles are -:
- <u>SKELETAL MUSCELES </u>
- <u>CARDIAC MUSCLES </u>
- <u>SMOOTH MUSCLES</u>
Explanation:
- <u>SKELETAL MUSCLES -: </u>There are long, cylindrical, and striated skeletal muscle cells. They are multi-nucleated, which means they have more than one nucleus. This is because from the fusion of embryonic myoblasts, they are created. Each nucleus controls the sarcoplasm's metabolic demands around it. There are high energy requirements for skeletal muscle cells, because they contain several mitochondria in order to generate adequate ATP. <u>Examples of skeletal muscles: arms and legs- </u>T<u>he muscles that belong to the arms and legs feature in pairs. Abdomen and Back- These muscles are connected to the various sets of skeletal muscles that run across the torso.</u>
- <u>CARDIAC MUSCLES -</u>: Cardiomyocytes have a short and narrow outline and are fairly rectangular. They are about 0.02 mm wide and 0.1 mm (millimetres) long, respectively. There are many sarcosomes in cardiomyocytes, which provide the required energy for contraction. Cardiomyocytes usually contain a single nucleus, unlike skeletal muscle cells. Cardiomyocytes, although they contain more sarcosomes, normally contain the same cell organelles as skeletal muscle cells.<u> example - cardiac muscle is present in heart. </u>
- <u>SMOOTH MUSCLES -:</u> Smooth muscle cells have a single central nucleus and are spindle-shaped. They range in length from 10 to 600 μm (micrometers), and are the tiniest type of muscle cell. In the expansion of organs like the kidneys , lungs, and vagina, they are elastic and therefore essential. As in cardiac and skeletal muscle, the myofibrils of smooth muscle cells are not aligned, meaning they are not striated, hence the term smooth. <u>example of smooth muscles -: Walls of blood vessels , Walls of stomach ,
Ureters , Intestines , In the aorta (tunica media layer), Iris of the eye. ,Prostate and Gastrointestinal Tract.</u>
Answer:
Both flowers and runners help a plant to reproduce.
Explanation:
Both flowers and runners help a plant to reproduce. While a flower help in sexual reproduction, a runner helps in asexual reproduction.
A flower has both male and female gamete at one place. When the pollen grains with in a flower reaches the female ovary, a new seed is produced which has the potential to develop into new plant. In case of runner (which is a stem), the tip of the stem has the potential to grow into a new plant