Sickle-cell anemia results from a point mutation in the HBB gene. The mutation results in the replacement of an amino acid that
has a hydrophilic R-group with an amino acid that has a hydrophobic R-group on the exterior of the hemoglobin protein. Such a mutation would most likely result in altered
In Sickle-cell anemia, the gene sequence of hemoglobin is changed in its sixth position due to the substitution of glutamate with valine.
So, since glutamate, an amino acid soluble in water due to its hydrophilic side chain is substituted with valine, an amino acid that has a hydrophobic side chain insoluble in water or bloodstream; the resulting hemoglobin protein is altered in structure (sickle shaped) and unable to bind and transport oxygen efficiently to the various body parts.
Water, carbon dioxide, and oxygen are among the few simple molecules that can cross the cell membrane by diffusion (or a type of diffusion known as osmosis ). Diffusion is one principle method of movement of substances within cells, as well as the method for essential small molecules to cross the cell membrane.
Use the vingear and baking soda experiment but change it to lemon and not vingear.
Explanation:
A chemical reaction takes place when vinegar and baking soda are mixed. One of the new substances formed is carbon dioxide gas. If the carbon dioxide gas is contained, the mass of the substances will stay the same according to the Law of Conservation of Mass. If the gas is allowed to escape, the mass will be less
