Many electrophilic aromatic halogenations require the presence of an aluminum trihalide as a catalyst. We generally acetylated the amino group as protection. Now, this acetanilide can be brominated at Ortho or para position. An atom that is attached to an aromatic system usually hydrogen is replaced by an electrophile is an organic reaction which is called Electrophilic aromatic substitution. There are what you called important electrophilic aromatic substitutions they are aromatic nitration, aromatic sulfonation, aromatic halogenation and acylation and alkylating Friedel-Crafts reaction. Aromatic bromination is an electrophilic aromatic substitution (EAS) reaction, which will require benzene to act as a nucleophile to acquire an electrophile. Therefore, any directing groups that activate the ring will make it react more quickly with respect to aromatic bromination. Acetanilide is a moderately-activated ring <span>having a decent EWG.</span>
The major limitations of Newlands' law of octaves were : (i) It was applicable to only lighter elements having atomic masses upto 40 u, i.e., upto calcium. After calcium, the first and the eighth element did not have similar properties
