Answer:
The correct option is: <em>a deficiency of dopamine in the substantia nigra.</em>
Explanation:
The substantia nigra is the principal site involved in the physiopathology of Parkinson´s disease.
Cells from this area degenerate and die progressively causing important degeneration in the central nervous system. The cells that die -with no known reason- are those that produce dopamine and proportionate dopaminergic innervation to the encephalon. In fact, almost all the symptoms exhibited by patients with the disease can be explained by the lack of dopamine in the substantia nigra.
This area uses the neurotransmitter to communicate neurons from the base ganglia. Ganglia are responsible of modulating and modifying movements.
The nigrostriatal system participates in planning and automatic execution of learned movements. When the ganglia activity decreases, so it does the amount and velocity of movements, something typical of the disease.
<em>The Jan. 21</em> total lunar eclipse will be the last one until May 2021, and the last one visible from the United States until 2022; the most recent total lunar eclipse previous to this one appeared in July 2018.
The warmer the water, the larger the water depths must be to form the hydrate. Deep inside he sea floor, however, the temperature is too high for the formation of methane hydrates because of the Earth's internal heat. Oxidation Many bacteria use methane to provide energy for their metabolism.
-worldoceanreview.com
IN THE LUMEN INSIDE OF THE ENDOPLASMIC RECTICULUM.
<u>Explanation:</u>
The endoplasmic recticulum is the continuous membrane system that forms that forms the more number of flattened within the cytoplasm of eukaryotic cells and performs the multiple process in the cell.
The immportant functions of endoplasmic recticulum is folding, synthesis, modification, ans transport of the protein. The lumen is the protein which is present in the endoplasmic recticulum.
The lumen of the endoplasmic recticulum is the area closed by the endoplasmic recticulum membrane, it is an extensive network of the membrane tubues, visicles, and flattened the cisternae found in the eukaryotic cells.