Answer: The classical complement pathway for complement activation is initiated by antigen-antibody complexes with the antibody isotypes IgG and IgM.
Explanation: The classical complement pathway typically requires antigen-antibody complexes (immune complexes) for activation (specific immune response), whereas the alternative pathway can be activated by C3 hydrolysis, foreign material, pathogens, or damaged cells.
After activation, a series of proteins are recruited to generate C3 convertase, which cleaves the C3 protein. The C3b component of the cleaved C3 binds to C3 convertase to generate C5 convertase, which cleaves the C5 protein. The cleaved products attract phagocytes to the site of infection and tags target cells for elimination by phagocytosis. In addition, the C5 convertase initiates the terminal phase of the complement system, leading to make appear the membrane attack complex. The membrane attack complex creates a pore on the target cell's membrane, inducing cell lysis and death.
<span>The answer is 45 miles per hour or even less. Most crashes occur at a speed of 45 miles per hour or even less, and most of these accidents occur close to our homes. These crashes may also be caused by different factors, such as being drunk or sudden occurrences that are not controllable, which is why it is best to precede with caution when driving at crowded areas.</span>
To determine the centroid of the object first moment of area is used.
To predict the resistance of a shape to bending and deflection which are directly proportional, second moment of area is used.
Answer:
the rate of turn at any airspeed is dependent upon the horizontal lift component
<u>Yes, work is done when a book falls of the table.</u>
This is because:
When the book falls, it's potential energy is converted into kinetic energy. As it reaches the floor down, this kinetic energy is converted to heat energy and sound energy due to the impact.
When a force is imposed on an object to cause displacement of that object, work is done on that object. For a force to do work on an object, there should be a displacement and this force should cause the displacement. So here, since the book falls from the table and causes the displacement of the book from the table to the floor. It is said that work is done.
Work can be given by the formula:
W = F • d
where F is the force and d is the displacement.
