Question

During a pertussis infection, the pathogenic bacterium Bordatella pertussis produces tracheal cytotoxin, which destroys cilia. Which of the following would most likely result from ciliary destruction?

Answer 1

Mucus would most likely accumulate in the respiratory tract as a result of ciliary destruction.

Pertussis (whooping cough) is a highly contagious respiratory tract infection. A severe hacking cough is followed by the a high-pitched breath intake that sounds like "whoop" in many people. Before the vaccine, whooping cough was thought to be a childhood disease. Whooping cough now primarily affects children who have not received the full course of vaccinations, as well as teenagers and adults whose immunity has waned.

Deaths from whooping cough are uncommon, but most commonly occur in infants. That is why it is critical for pregnant women and others who will have close contact with an infant to be immunized against whooping cough. The best way to avoid pertussis is to get vaccinated. Check that you and your loved ones have received their pertussis vaccines.

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