If ADP (two phosphates) were hydrolyzed to AMP, how would you expect this reaction to compare with the hydrolysis of ATP to AMP?
ADP and ATP are both hydrolyzed to give AMP, the only difference remains in the side product formed which is pyrophosphate for ATP hydrolysis and inorganic phosphate for ADP hydrolysis.
What is ATP hydrolysis?
Adenosine triphosphate (ATP) contains highly energetic phosphoanhydride bonds that, when broken, such as occurs in muscles, release chemical energy through a catabolic reaction process called ATP hydrolysis. Adenosine diphosphate (ADP) and an inorganic phosphate are the end result (Pi). Adenosine monophosphate (AMP), energy, and another inorganic phosphate can all be produced by further hydrolyzing ADP (Pi). The final step in the energy chain from food or sunlight to useful work like muscle contraction, the creation of electrochemical gradients across membranes, and life-sustaining biosynthetic processes is ATP hydrolysis.
<u>ATP + H 2 O → AMP + Pyrophosphate(PP)ADP + H 2 O → AMP + Inorganic Phosphate(Pi) </u>
Thus, ADP and ATP are both hydrolyzed to give AMP, the only difference remains in the side product formed which is pyrophosphate for ATP hydrolysis and inorganic phosphate for ADP hydrolysis.
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