Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Three of the five leading causes of death from communicable diseases globally are the Lower respiratory infections, TB, HIV. That is option C.
<h3>The top global leading causes of death in communicable diseases</h3>
Communicable diseases are those diseases that can be transmitted from one person to another through close contact or transfer of body fluids from an infected individual.
According to World Health Organizations, the five communicable diseases that has caused highest death rates are :
- Lower respiratory infections: This has caused about 3.4 million deaths.
- HIV/AIDS: This has caused about 2.6 million deaths.
- Diarrheal diseases: this has caused about 1.8 million deaths.
- Tuberculosis(TB): This has caused about 1.6 million deaths. and
- Malaria: This has caused about 1.1 million deaths.
Therefore, three of the five leading causes of death from communicable diseases globally are the Lower respiratory infections, TB, HIV.
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brainly.com/question/25476918
Answer:
It is the cardiac output.
Explanation:
Heart rate x stroke volume = cardiac output.
The cardiac output is the final outcome of all factors that influentiate the ventricular activity (heart rate, heart contractility, and the phenomenon of precharge and postcharge).
Answer:
Yes breakfast does have the energy that you need throughout the day for example i have skipped breakfast and i was very tired throughout the day. you should eat breakfast as a necessity every single day
Explanation:
Answer:
Meal planning / prepping
Explanation:
This will help the client be able to see beforehand how much of each proportion he should be getting to maintain a balanced diet.
